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Cow snot could protect from STIs including HIV and herpes

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Daily Mail: A lubricant made with cow mucus could protect against HIV and herpes, scientists say.

Lab experiments proved the gel, which would be applied in the same way as shop-bought ones currently, could beat the sexually transmitted infections.

Human cells first treated with the lubricant were 70 to 80 per cent less likely to get infected with HIV and herpes.

The researchers said their ‘promising’ creation could slow the spread of STIs, if it is made publicly available following further tests.

Mucus — found in the nose, throat and oesophagus — traps bacteria, viruses and dirt to stop them reaching and damaging the lungs.

Mucus is also packed with protective proteins that help break down these germs and force them out of the body through coughs and sneezes.

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The main component of mucus — a protein called mucin — is thought to have antiviral properties.

The researchers, from the KTH Royal Institute of Technology in Stockholm, Sweden, examined whether mucus could stop STIs from getting into the body and spreading in the same way.

The team, led by researcher Hongji Yan, extracted mucus from cow salivary glands, which they turned into a mucin-based lubricant.

In a petri dish, the team then exposed human epithelial cells, those which line the inner surface of the body, to HIV-1 — the most widespread version of the virus — or HSV-2, which causes genital herpes.

Half of the cells had been treated with the gel beforehand.

The researchers removed the gel from the cells that had been treated with it and left them exposed to the viruses for two days.

The results, published in the scientific journal Advanced Science, show that only 30 per cent of cells mixed with the lubricant and HIV became infected.

For comparison, 100 per cent of human cells exposed to just HIV became infected.

Meanwhile, just 20 per cent of human cells mixed with the gel and HPV became infected, compared to all of those exposed to just the virus.

The researchers said this shows that the gel stopped the transmission of HIV by 70 per cent and herpes by 80 per cent.

The lubricant works by ‘trapping’ the virus particles and clearing them from the body — replicating the ‘self-healing’ function that mucus naturally provides in the body, according to the scientists.

The mucin in the gel also hinders the activation of immune cells, which are known to fuel the replication of HIV in the body, the team said.

And if the lube was to be used by people, there is little risk of side effects or antiviral resistance because mucin is already found in the body, according to the researchers.

Mr Yan said the gel could help people ‘take greater control of their sexual health’.

He said: ‘It could offer protection when condom protection is not an available option, or even as back-up protection in case of condom failure or incorrect use.

‘It could be used in both female-to-male sex and male-to-male sex.’

As it stands, people are advised to use condoms during sex and to get tested before having sex with a new partner to avoid the spread of STIs.

Some 3,000 people were diagnosed with HIV in the UK last year, while more than 20,000 in England were diagnosed with genital herpes.

Around 35,000 people are diagnosed with HIV every year in the US, while 570,000 are thought to catch genital herpes.

STI rates had been gradually creeping up before Covid hit but lockdowns saw rates naturally decline, given people were less able to meet up for casual sex and flings.

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REQUEST FOR EXPRESSIONS OF INTEREST

(CONSULTING SERVICES – INDIVIDUAL SELECTION)

 

OECS MSME Guarantee Facility Project

Loan No.: IDA-62670, IDA-62660, IDA-62640, IBRD-88830, IDA-62650

Assignment Title: Senior Operating Officer (SOO)

Reference No. KN-ECPCGC-207852-CS-INDV

 

The Governments of Antigua and Barbuda, Commonwealth of Dominica, Grenada, St. Lucia and St. Vincent and the Grenadines have received financing in the amount of US$10 million equivalent from the World Bank towards the cost of establishing a partial credit guarantee scheme, and they intend to apply part of the proceeds to payments for goods, and consulting services to be procured under this project. 

The consultant will serve as the “Senior Operating Officer (SOO)” for the ECPCGC and should possess extensive knowledge of MSME lending with some direct experience lending to Micro, small and medium-sized businesses, knowledge of the internal control processes necessary for a lending operation and the ability to design and implement risk mitigation procedures. The ideal candidate should possess an Undergraduate Degree from a reputable college or university, preferably in Business, Accounting, Banking or related field, with a minimum of 5 years’ experience in lending, inclusive of MSME lending. The initial employment period will be for two years on a contractual basis. Renewal of the contract will be subject to a performance evaluation at the end of the contractual period. The assignment is expected to begin on September 30th, 2021.  The consultant will report directly to the Chief Executive Officer of the ECPCGC.

The detailed Terms of Reference (TOR) for the assignment can be viewed by following the attached link below. 

 

https://bit.ly/3iVannm

 

The Eastern Caribbean Partial Credit Guarantee Corporation (ECPCGC) now invites eligible “Consultants” to indicate their interest in providing the Services. Interested Consultants should provide information demonstrating that they have:

  • An Undergraduate Degree from a reputable college or university, preferably in Business, Finance, Banking or related field; and
  • Minimum of 5 years’ experience in MSME lending. Applicants should also have:
  • The ability to design and implement risk management procedures 
  • Extensive knowledge of MSME lending with some direct experience lending to small and medium-sized businesses
  • Extensive knowledge of MSME banking operations
  • Knowledge of the internal controls necessary for a lending operation and the ability to design and implement risk management procedures
  • Experience developing and presenting information in public, including responding to questions in real-time
  • Experience lending to MSMEs located in the ECCU
  • Knowledge of marketing and communicating with the MSME sector
  • Ability to draft procedures to be used in a lending operation
  • Familiarity with the mechanics of a loan guarantee program
  • Exceptional written, oral, interpersonal, and presentation skills, and
  • Proficiency in the use of Microsoft Office suite.

The attention of interested Individual Consultants is drawn to Section III, Paragraphs 3.14, 3.16, and 3.17 of the World Bank’s Procurement Regulations for IPF Borrowers July 2016, [revised November 2017] (“Procurement Regulations”), setting forth the World Bank’s policy on conflict of interest. A Consultant will be selected in accordance with the Approved Selection Method for Individual Consultants set out in the clause 7.34 of the World Bank Procurement Regulations for IPF Borrowers. 

 

Further information can be obtained at the address below during office hours 0800 to 1700 hours:

Eastern Caribbean Partial Credit Guarantee Corporation

Brid Rock, Basseterre,

St. Kitts.

Expressions of interest must be delivered in a written form by e-mail by August 11th, 2021, to [email protected]

 

For further information, please contact:

Carmen Gomez-Trigg                                                            Bernard Thomas

Chief Executive Officer                                                          Chief Financial Officer

Tel: 868-620-8144                                                                  Tel: 869-765-2385

Email: [email protected]                                          [email protected]